Dentsply Sirona and Pearl have announced a new partnership that brings AI-supported analysis of 2D radiographs directly into the DS Core platform. The collaboration enables users of Dentsply Sirona’s DS Core to access Pearl’s FDA-cleared AI software, Second Opinion®, as part of their existing imaging workflow.
With this integration, 2D radiographic images captured within the DS Core environment are automatically available for analysis by Second Opinion®. The AI tool is designed to assist clinicians in identifying anatomical landmarks and detecting potential pathologies such as incipient caries or early bone loss. AI-generated annotations and measurements are incorporated into the images, providing an additional layer of visual information that can support both diagnostic decisions and patient discussions.
“This collaboration with Dentsply Sirona brings our vision of accessible, trustworthy dental AI to an even broader global audience,” said Ophir Tanz, CEO of Pearl. “By embedding Second Opinion directly into DS Core, we’re giving clinicians seamless access to AI insights that strengthen their diagnostic confidence, improve patient communication, and ultimately elevate the standard of care across every practice.”
The integration is facilitated by the DS Core API (application programming interface), which allows third-party applications—including imaging software, PMS, and lab systems—to securely connect with DS Core. According to Dentsply Sirona, this infrastructure supports more connected workflows and enables practices to integrate digital tools more efficiently.
“Our goal is to foster an open, collaborative ecosystem where innovation thrives. With its open architecture, DS Core empowers partners and developers to build integrated solutions that streamline diagnosis, enhance patient outcomes, and optimize clinical workflows,” said Max Milz, Group VP of Connected Technology Solutions at Dentsply Sirona. “Following the launch of our own AI-powered 3D x-ray capabilities on DS Core, this integration marks another important step toward making advanced diagnostics more accessible and connected—underscoring our commitment to seamless workflows and better care through shared progress.”
For clinicians and IT partners interested in developing or configuring integrations with DS Core, the DS Core API and its documentation are available at: https://open.dscore.com